Best ant and roach spray

Eliminate infestations in a snap, and maintain pest control with the best ant and roach spray for the job.

best ant and roach spray
dead cockroach upside down surrounded by tiny black ants trying to carry it away
(Image credit: iGggaz/Shutterstock)

Sometimes, pest control requires a different approach than just placing traps and hoping for the best. For example, ants and roaches are the most common pests for household infestations, so it stands to reason that folks will gravitate toward the best possible ant and roach spray. Our best overall ant and roach spray is made by Ortho, a well-known brand for effective pest control. Pro exterminators use it, but so can you; it's formulated to provide a barrier of protection. Apply it to your home's foundation, entrances, and walls, for treatment capable of lasting up to three months. You'll find a few more options below, including a fogger and naturally-based sprays—see which ant and roach spray is right for you.

Best overall

ant and roach spray

(Image credit: Amazon)

Ortho Home Defense insect killer for indoor and perimeter

Staff pick

If you're looking for thorough, lasting protection, then Ortho's Home Defense barrier spray can last for up to 1 year.

Pros:

  • Less hand fatigue with Comfort Wand
  • No pumping
  • Keeps bugs out with lasting barrier
  • No staining or odor

Cons:

  • Pesticide based, not natural
  • Barriers only work on non-porous surfaces
  • Not for infestations

Ortho's spray is focused on keeping pests out of your home long-term rather than spot-treating infestations. It contains two pesticides—bifenthrin and zeta-cypermethrin. These compounds kill spiders, ants, and roaches on contact and repel over 130 additional insects. Better yet, you can use it to establish barriers lasting up to one year around internal and external entrances to your home, including basements, garages, and foundation perimeters. A 4-inch wide barrier is sufficient for kitchens, windows and doors, basements, and bathrooms. Still, you'll want to widen that band to about 1 foot for outdoor areas, including your patio, garage, and foundation's perimeter. 

Best value

ant and roach spray

(Image credit: Amazon)

Raid aerosol ant and roach spray with essential oils

No chemical stink

Lemongrass and geraniol are powerful deterrents for ants, roaches, and many other bugs, and Raid uses them to great effect. 

Pros:

  • Lemongrass essential oil
  • Pine-derived geraniol
  • Fast kill for 20+ household pests
  • Aimed at crawling insects

Cons:

  • Doesn't work on fire ants and harvester ants
  • Sprays single stream, not mist
  • Avoid if you/your family have respiratory issues or allergies

Raid's well known for their extermination prowess, when it comes to creepy crawlies of all sorts. They've ditched the heavy pesticides this time around though, with their aerosol ant and roach spray infused with essential oils. Lemongrass essential oil is commonly used in natural bug repellents, as is geraniol to create effective protection with minimal chemical exposure (e.g. sprays with DEET or permethrin). A downside to this particular Raid product is its spray nozzle. It emits a thin stream that's tough to aim, rather than a more generalized mist. You'll also want to avoid using this spray on hardwood floors and house plants because the mineral oil in its formula makes it slippery, and can cause phytotoxicity.

Full coverage

ant and roach spray

(Image credit: Amazon)

Hot Shot indoor ant and roach fogger with odor neutralizer

Gets every cubic foot

Hot Shot's 6-pack of foggers might not fix your fire ant problem, but it will take care of just about any other ant (or bug) it comes across.

Pros:

  • Bonus odor-neutralizing effect
  • 2,000 square-foot coverage per can
  • Contact kill for 2 months
  • Clear formula, no residue

Cons:

  • Indoor use only
  • Empty house (family, pets) before fogging
  • Turn out pilot light in stove before use

Why spray down every inch of your home by hand when you can use a can of Hot Shot's fogger mist? Also called "bug bombs," foggers exterminate by releasing a fine mist capable of sinking into every nook and cranny it settles upon. The formula's aimed at more than ants and roaches, but it's powerful enough to wipe out wasps, murder pantry moths, and finish off every last flea. Fire ants, as usual, will probably persist past treatment, despite formulation with powerful tetramethrin and cypermethrin. Unfortunately, there are quite a few non-negotiable safety measures to take before fogging your home. All residents, including pets (especially birds), must be vacated for a few hours at a bare minimum. Furthermore, you can't let it contaminate your food or stick to your floors (so you'll have to remove or cover it). 

Multiple scents

ant and roach spray

(Image credit: Amazon)

Wondercide indoor pest control spray for home and kitchen

Prevent and treat

Say goodbye to ants, roaches, and all sorts of flying, crawling, biting, and stinging insects with Wondercide's plant-derived biopesticide spray.

Pros:

  • 32-ounce bottle treats up to 400 square feet
  • Four natural fragrances
  • Plant-derived
  • Kills and repels fleas, scorpions, and silverfish too

Cons:

  • Not fast-acting

Rosemary, cedarwood, lemongrass, and peppermint are at the forefront of Wondercide's quartet of botanically-scented sprays. The benefits of aromatherapy and effective, plant-based biopesticide join forces to eradicate and prevent all sorts of unwanted insectile interlopers. Cedar oil is a primary ingredient of the Wondercide formula. It works by blocking a neurotransmitter in insects that control their breathing, heart rate, and movement. Wondercide also acts as a biphasic flea treatment for stain-free eradication in carpeting, bedding, flooring, and furniture. Using it is simple, too: within a seven to ten-day period, apply the spray everywhere you see signs of infestation. Then, for maintenance, repeat monthly and enjoy your bug-free, nicely scented home. 

Spicy-sweet scent

ant and roach spray

(Image credit: Amazon)

Dr. Killigan’s Six Feet Under non-toxic insect spray

Fun name, fantastic results

The wryly-named Dr. Killigan's "Six Feet Under" spray has whimsical packaging and a cinnamony-sweet fragrance, disguising a potent recipe for total extermination.

Pros:

  • Topical flea and tick control for pets
  • Pleasant fragrance
  • Non-toxic

Cons:

  • Poor choice for dealing with bed bugs

Dr. Killigan's bug-killing spray is a genuinely pet-safe and non-toxic option, with a humorously dark aesthetic and subtly spicy smell. Clove, cottonseed, and cinnamon oils come together to make a surprisingly efficient insecticide spray capable of eliminating more than just ants and roaches from your abode. Conveniently, wily fruit flies, mosquitoes, and silverfish will fall victim to this spray, too. It can even be used directly on your pets' fur to kill fleas and ticks at all stages of life—safely and naturally. There are no toxic fumes here, either; the formula smells like a snickerdoodle rather than stifling gases. 

Bottom line

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So, there you have it—a selection of the best ant and roach sprays I could find. This list does skew toward the all-natural and bio-degradable formulas; that's because they're a significant percentage of your options these days. Ortho's ant and roach spray, our staff pick, is formulated with pesticides instead. When used correctly, it's safe to use inside and outside your home. It's aimed at infestation prevention and control via barrier-making and killing insects on contact.

Suppose you'd rather err on the plant-derived, bio-degradable side when buying bug sprays. Wondercide's ant and roach spray is a great example; it kills more than just those two species, and its active ingredient is all-natural. Cedar oil damages insects at the neurological level while smelling like a forest and is non-toxic to humans and pets when used correctly. You can choose between four bold, botanical scents as well. 

Why trust us?

At GardeningEtc, we recommend the best products to enhance your life. As expert curators, we handpick products based on quality and usefulness to positively impact your day-to-day, from cart to doorstep. We take our responsibility seriously — testing products, reading reviews, and sourcing knowledgeable outlets to ensure our selections are worthy of your time and money. We deliver detailed product overviews, balancing objective information with subjective opinions, so making the best choice for your home and lifestyle is as easy as possible.

Freelance Writer, AOP

Lili Angrisano is a freelance contributor for both GardeningEtc and Real Homes. In her spare time you will typically find her designing her next cosplay, conquering her 700+ book (and counting!), reading the latest release on her Kindle library, or tending to the many plants and flowers in her much-loved apartment garden.